Methylene Blue BioMethylene blue

Methylene Blue Bio / Evidence

Evidence

Methylene blue: animal studies vs human evidence, explained
Most mitochondrial and longevity claims for methylene blue come from rodent studies, not humans. Here's what's actually proven vs extrapolated, and why it matters.
Methylene blue before and after claims: what's real evidence
Before/after photos and reviews for methylene blue can't show mitochondrial or cognitive change. Here's what's FDA-approved, what's off-label, and what's just anecdote.
Methylene blue clinical trials: what the evidence shows
FDA approved it in 1891 for methemoglobinemia. Nootropic and anti-aging claims rest on small trials and animal studies. Here's what's actually proven.
Methylene blue human studies: what the evidence really shows
A review of actual human trials on methylene blue for cognition, mitochondria and mood, versus its one FDA-approved use for methemoglobinemia.
Methylene blue mechanism of action, explained simply
Methylene blue works as an electron cycler and reversible MAOI at low doses. FDA-approved for methemoglobinemia at 1-2 mg/kg IV; other uses are off-label.
Methylene blue results: what the research actually shows
FDA approved methylene blue for one thing: methemoglobinemia. Energy, focus, and anti-aging claims rest on small trials and lab data. Here's the real evidence.